Icatibant

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

C01EB19

CAS registry number (Chemical Abstracts Service)

0130308-48-4

Chemical Formula

C59-H89-N19-O13-S

Molecular Weight

1304

Therapeutic Categories

Treatment of hereditary angioedema

Bradykinin receptor B2 antagonist

Chemical Names

(R)-arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-thienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isochinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolin-3-yl)carbonyl]-(S)-arginin (IUPAC)

(R)-Arginyl-(S)-arginyl-(S)-prolyl-(2S,4R)-(4-hydroxyprolyl)glycyl-(S)-[3-(2-thienyl)alanyl]-(S)-seryl-(R)-[(1,2,3,4-tetrahydro-3-isoquinolyl)carbonyl]-(2S,3aS,7aS)-[(hexahydro-2-indolinyl)carbonyl]-(S)-arginine (WHO)

D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl-L-arginine

L-arginine, D-arginyl-L-arginyl-L-prolyl-trans-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl-D-1,2,3,4-tetrahydro-3-isoquinolinecarbonyl-L-(2α,3abeta,7abeta)-octahydro-1H-indole-2-carbonyl- (CAS)

Foreign Names

• Icatibantum (Latin)
• Icatibant (German)
• Icatibant (French)
• Icatibanto (Spanish)

Generic Names

• HOE 140 (IS)
• Hoec (IS)
• Hoechst 140 (IS)
• JE-049 (IS: Jerini)
• Icatibant Acetate (OS: USAN)

Brand Names

• Firazyr
  Jerini, Greece; Jerini, Luxembourg; Drac, Switzerland; Jerini, Austria; Jerini, Germany; Jerini, Spain; Jerini, Finland; Jerini, United Kingdom; Jerini, Sweden; Shire, France

International Drug Name Search

Glossary

CAS	Chemical Abstracts Service
IUPAC	International Union of Pure and Applied Chemistry
IS	Inofficial Synonym
OS	Official Synonym
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)
USAN	United States Adopted Name
WHO	World Health Organization

Click for further information on drug naming conventions and International Nonproprietary Names.